PEA: How to Combat Pain and Inflammation Naturally

PEA (Palmitoylethanolamide): how to fight pain and inflammation naturally

Palmitoylethanolamide (PEA) is a substance naturally produced by our cells to counteract inflammation and pain.

Known since 1957, its effectiveness has been deepened thanks to the research of Nobel Prize winner Rita Levi Montalcini. PEA is also a natural aid for the immune system.

How exactly does PEA produced by our body work?

As Rita Levi Montalcini explained in 1993, PEA is produced by the cell membranes of our body, with a request mechanism, which is activated in situations or pathologies that trigger inflammation, a neuropathic damage (which concerns the Nervous System at some level) and alterations of the immune system.

This natural substance therefore helps to counteract the conditions that cause inflammation and pain.

Palmitoylethanolamide (PEA) is an extraordinary substance that helps to “extinguish” the fire of inflammation

It acts by modulating the substances produced by the inflammatory cells called Mastocytes, which are the cause of both inflammatory and neuropathic pain.

In addition, science shows that PEA binds to Cannabinoid receptors (responsible for the painkiller action of the substances contained in Cannabis); however, it acts on a specific receptor, like a key that only opens a specific door.

Thus determining only the positive effects, without any of the side effects typical of painkillers and anti-inflammatory drugs.

What benefits can you get from taking PEA?

Numerous studies, now hundreds, easy to find in the most authoritative scientific databases, explain and demonstrate that PEA is able to facilitate the positive, protective and self-repairing responses that our body activates when needed (nerve damage, immune system problems, tissue inflammation, etc.)

The conditions for which its effectiveness is now widely accepted are:

Trigeminal neuralgia
Post-herpetic neuralgia (Shingles)
Back pain (Sciatica, Radiculopathy)
Neck pain (cervico-brachialgia)
Rheumatic pain (Osteoarthritis, Osteoarthrosis)
Carpal tunnel syndrome
Cubital tunnel syndrome
Tarsal tunnel syndrome
Common peroneal nerve neuropathy
Peripheral neuropathies
Polyneuropathies
Long-Covid syndrome
Chronic inflammatory bowel diseases
Chronic pelvic pain
Vulvodynia and pudendal nerve neuropathy
Bladder pain syndrome

How PEA can help fight nerve compression pain

Nerve compression pain includes many forms of Lumbosciatica and Cervicobrachialgia in addition to tunnel syndromes (carpal and tarsal). These are due to nerve compression for different reasons, such as a lumbar or cervical hernia or a reduction in the space of the tunnel crossed by the nerve. Pain is caused by several factors, such as inflammation and chronic injury of the peripheral nerve.

An important study published in the Journal of Pain Research analyzed the effectiveness of PEA in 636 patients suffering from carpal tunnel syndrome and pain due to lumbosciatica. The results were very positive, with a significant reduction in pain after 21 days of treatment and a consequent improvement in the patients’ quality of life.

PEA has been shown to significantly improve pain and inflammation symptoms without side effects

However, it is important to remember that even natural substances must be used under medical supervision, as the dosage and dosages vary according to the need and the individual patient.

Learn more about PEA and how it can help improve your health naturally!